Tharaka University repository: Recent submissions
Now showing items 1241-1260 of 4288
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Hiv-Aids and Single Mothers Livelihoods Security in Slum Houeseholds: Targeting Procedures in Safety-Net Programmes in Kenya.
(2018-10)Single mothers coping mechanisms with the effects of HIV and AIDS in slum settlements are rarely analysed and documented.The numerous vibrant anti-Aids campaigns are no longer visible in slums. Does this imply that a ... -
HIV and AIDS Silence: The Coping Mechanism of the Youth in Poor Households in Kenyan Slums
(2018-04)There is no doubt it is all silent! HIV and AIDS are no longer the threatening health diseases that dominated the local and international daily news! Are HIV and AIDS no longer imminent health challenges, particularly ... -
Avega Interventions and Post Traumatic Growth Among Genocide Widows in Nyarugenge District, Rwanda.
(2019-10)The purpose of this study was to examine the effects of AVEGA interventions on posttraumatic growth among genocide widows in Nyarugenge District in Rwanda. The study was guided by Abraham Maslow's theory of hierarchy ... -
Social Workers’ Knowledge Level Influence and Child Protection Approaches in Kajiado North Sub-County, Kajiado County, Kenya
(2020-06)The study’s objective was to establish the extent to which social workers’ knowledge level influences child protection interventions in Kajiado North Sub County. The study was guided by Competence Based curriculum ... -
Father Absenteeism on Social Vulnerability Among Modern Families in Kenyan Urban Households: A Case Study of Kibra County, Nairobi, Kenya
(2017-09)The study set out to investigate the impacts of father absenteeism on social vulnerability among Kenyan modern households in Kibra County. Interviews and observation were predominantly employed in data collection, with ... -
Experiential Learning and Malaria Intervention Volunteers Capacity Development: Lessons From Kombo North District in Gambia
(2017-07)Global distribution of per-capita gross domestic product indicates a striking correlation between malaria and poverty, and malaria-endemic countries have lower rates of economic growth. This study investigated the role ... -
Cement Manufacturing Companies’ Corporate Social Responsibility and Pastoralists Livelihoods Security in Kitengela Ward, Kajiado County, Kenya
(2019-10)The purpose of this study was to examine Cement Manufacturing Companies Corporate Social Responsibility and Pastoralists Livelihoods Security in Kitengela, Kajiado County, Kenya. The specific objectives that the study ... -
Parental Absenteeism: Child Nurturance and Socialization Impedes in Bibirioni Ward, Kiambu County, Kenya
(2020-02)Undoubtedly, the changing dynamics of the families from heterogeneous to homogeneous structure, the effects of globalization, technology, economy and social changes have adversely affected parenting. Parents have ... -
HIV/AIDS: Household Coping Mechanisms of the Poor in Kenya Slums
(2018)The National silence and persistent global disinterest in HIV and AIDS is worrying! Is this an implication that a proper cure of this scourge is now discovered and readily in use? There is no doubt the World has achieved ... -
Household Livelihoods Survival Mechanisms and Women Enterprise Fund Up-take in Isiolo County, Kenya
(2020-05-13)The general public and government social transformation agents alike assume that all Women have equal access to Development safety-net funds. Isiolo County, though a predominantly pastoralist region, has motivated women ... -
Albinism, Witchcraft, and Superstition in East Africa: Exploration of Bio-cultural Exclusion and Livelihood Vulnerability
(2014-04-16)Profuse media reports and discourse on the plight of Persons with Albinism (PWA) in East Africa in the recent times raise the question of livelihood security of a minority group. PWA constitutes a group of people that are ... -
Risk Management Approaches and Construction Project Performance in The National Construction Industry Council, Malawi
(2021-09)The article examines risk management approaches and construction project performance in the National Construction Industry Council of Malawi (NCIC). Established in 1996, NCIC is a mother body in the construction industry, ... -
Participatory Learning and Action for Enhanced Sugarcane Farming Performance in Kakamega County, Kenya
(2019-10)The study aimed at establishing the significance of participatory learning and action (PLA) on the performance of sugarcane farming project in Kakamega County, Kenya. The study adopted a Mixed Research Design, and was ... -
Water Resource Management Approaches and Community Livelihoods in Saku Sub-County, Marsabit County, Kenya
(2020-06)Water is a crucial resource to human and livestock. The management of this scarce resource is critical in the face of recurrent droughts and growing water scarcity, especially in arid and semi-arid areas. The aim of this ... -
Stereoselective synthesis of fused tetrahydroquinazolines through one-pot double [3 + 2] dipolar cycloadditions followed by [5 + 1] annulation
(2016-10)The one-pot [3 + 2] cycloaddition of an azomethine ylide with a maleimide followed by another [3 + 2] cycloaddition of an azide with the second maleimide gives a 1,5-diamino intermediate which is used for a sequential ... -
[3+2] Cycloaddition-based one-pot synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold
(2017-01)Three-component [3+2] cycloaddition followed by reduction and lactamization has been developed as a one-pot methodology for diastereoselective synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold. -
One-pot and catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates†
(2017)A method for the catalyst-free synthesis of pyrroloquinolinediones and quinolinedicarboxylates is develo ped through a one-pot synthesis involving denitrogenation of azide, benzisoxazole formation, aza-Diels– Alder ... -
Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors
(2018)The simultaneous inhibition of polo-like kinase 1 (PLK1) and BRD4 bromodomain by a single molecule could lead to the development of an effective therapeutic strategy for a variety of diseases in which PLK1 and BRD4 are ... -
[3 + 2] Cycloaddition and Cascade Radical Reactions for the Synthesis of Trifluoromethylated Tetrahydrobenzodiazepin-3-ones
(2019-04-01)A reaction sequence involving three-component [3 + 2] cycloaddition of azomethine ylides followed by CuI catalyzed cascade trifluoromethyl radical addition and cyclization is developed for diastereoselective synthesis of ... -
Development of Dimethylisoxazole-Attached Imidazo[1,2‑a]pyridines as Potent and Selective CBP/P300 Inhibitors
(2021)The use of epigenetic bromodomain inhibitors as anticancer therapeutics has transitioned from targeting bromodo main extraterminal domain (BET) proteins into targeting non-BET bromodomains. The two most relevant non-BET ...